Bioinformatics

Bioinformatics has its roots vaguely seated in the early 1980s, a time when personal computers began appearing in research laboratories and researchers began recognizing that those computers could be used as tools to organize, analyze and visualize their data. rogress and interest in plant genomics have been accelerating since the time in late 2000 when the genome of Arabidopsis thaliana was published. Since then many genome sequencing projects have been undertaken that include poplar (Populus), grape (Vitis), the moss Physcomitrella, the biflagellate algae Chlamydomonasand several globally crucial crop plants such as corn (Maize) and rice (Oryza). However, as we have witnessed on numerous occasions, determining the sequence of a genome is only the first step toward understanding genome organization, gene structure, gene expression patterns, disease pathogenesis and a host of other features of both scientific and commercial interests. Computational tools of genomic annotation and comparative genomics must be applied to gain a useful understanding of any genome. Drug designing by the use of bioinformatics tools and software is on the height. Now-a-days CADD (Computer-Aided Drug Design) is very much helpful in discovering new drug. In plant biology, these tools are helpful in improving crop, improving nutrition quality. It also helps in studying medicinal plants with the help of proteomics, genomics, transcriptomics, and helps in improving the quality of traditional medicinal material. Genomics helps in providing massive information to improve the crop phenotype. Bioinformatics have tools to analyze biological sequences like DNA, RNA and protein sequences.

TSB is working with its partners in Northern Ireland and Scotland to make £2.75 million ($4.6 million) available to small businesses involved with bioinformatics and other sectors. The cash will be divvied up into £50,000 to £150,000 awards to help startups run feasibility studies. The global bioinformatics market is estimated to reach $4.2 billion by the end in 2014 and is poised to reach $13.3 billion by 2020 at a CAGR of 20.9% from 2015 to 2020. In 2015, North America is expected to account for the largest share of the bioinformatics market, followed by Europe. Both markets are estimated to register double-digit growth rates over the next five years.

  • Plant genome projects and application of bioinformatics tools in structural and functional genomics
  • Comparative analysis of plant genomes using molecular markers
  • Genetic map construction using molecular markers
  • QTL mapping in plants
  • Genetic algorithms in QTL mapping
  • DNA array technology
  • Genome sequence linking to phenotypes
  • Tools of transcriptomics, proteomics and Metabolomics

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